The exact cause of rosacea remains unclear, which makes it difficult to treat effectively. Although several medications are used, many provide only partial or temporary improvement. Differences in how rosacea severity is measured also make it challenging to compare treatment outcomes across studies. Therefore, there is a need for a consistent and reliable evaluation system to properly assess new therapies.
Patients often report different triggering factors, but no single standardized cause has been confirmed. The fact that rosacea responds to drugs with different mechanisms suggests that it likely has multiple underlying causes.
Topical ivermectin has become an increasingly promising treatment option. It may be effective because it combines anti-inflammatory effects with antiparasitic activity, targeting Demodex mites that are thought to inhabit the hair follicles and sebaceous glands of affected patients.
